GLOSSARY

Skin Science Glossary

The language of
laser skin care.

A comprehensive reference glossary of the scientific and clinical terms used in laser skin care, photomedicine, and aesthetic technology — curated by the OYAY LAB science team.

A

Ablative Laser

A laser treatment that removes (ablates) the outer layer of skin (epidermis). Ablative lasers — such as CO₂ (10,600nm) and Er:YAG (2940nm) — produce dramatic resurfacing results but require significant recovery time (typically 5–14 days of redness, peeling, and social downtime). OYAY LAB home devices use non-ablative technology, which achieves dermal remodeling without removing the skin surface. See also: Non-Ablative Fractional Laser.

ATP (Adenosine Triphosphate)

The primary energy molecule in living cells. Laser photobiomodulation at specific wavelengths (such as 940nm in the OYAY LAB RelaxLight) stimulates mitochondrial cytochrome c oxidase to increase ATP production, improving cellular function, reducing inflammation, and accelerating tissue repair.

C

Chromophore

A molecule in biological tissue that selectively absorbs light at specific wavelengths. The primary skin chromophores relevant to laser treatment are: melanin (pigment; absorbs visible and near-UV light), oxyhemoglobin (blood; absorbs at ~418nm, ~542nm, ~577nm), water (absorbs strongly in mid-infrared; 1450nm, 1927nm), and collagen (absorbs UV and some visible light). OYAY LAB wavelengths are selected to maximally target the intended chromophore for each treatment purpose.

Collagen (Type I & Type III)

The most abundant structural proteins in human skin. Type I collagen forms thick, organized fibers that provide tensile strength and firmness. Type III collagen is a finer fibrillar network associated with wound healing and early tissue repair. Skin aging is characterized by a decline in both collagen quantity and structural organization. Non-ablative fractional laser treatments like those delivered by OYAY LAB Iris Ice Plus stimulate fibroblasts to synthesize new Type I and III collagen in the dermis.

Cutibacterium acnes (C. acnes)

The anaerobic gram-positive bacterium primarily responsible for inflammatory acne vulgaris. C. acnes inhabits the sebaceous follicles of the skin, metabolizes sebum, and triggers an inflammatory immune response. The OYAY LAB Nova device targets C. acnes using 830nm near-infrared laser (deep bacterial destruction) and 415nm blue light (surface porphyrin activation), eliminating bacteria without antibiotic resistance concerns.

D

Dermis

The layer of skin beneath the epidermis, composed primarily of collagen, elastin, fibroblasts, blood vessels, and nerve endings. The dermis is the target of most therapeutic laser treatments — including OYAY LAB Iris Ice Plus (1450nm), Dora (1927nm), and RelaxLight (940nm). Dermal collagen content and organization directly determine skin firmness, elasticity, and the visibility of wrinkles.

E

Elastin

A highly elastic protein in the dermis that allows skin to return to its original shape after stretching or compression. Elastin production declines with age and UV exposure; once damaged, elastin fibers do not regenerate effectively. Non-ablative fractional laser treatments stimulate limited elastin remodeling alongside collagen neogenesis, contributing to improved skin resilience.

Epidermis

The outermost layer of skin, approximately 0.1mm thick, composed primarily of keratinocytes. The epidermis provides the physical barrier function of skin. In non-ablative laser treatments like those used in OYAY LAB devices, the epidermis is preserved — energy passes through it to reach the dermis without causing surface damage. This is in contrast to ablative laser treatments, which deliberately remove the epidermis.

F

Fibroblast

The primary collagen-producing cell of the dermis. Fibroblasts synthesize collagen, elastin, hyaluronic acid, and other extracellular matrix components. Laser-induced thermal micro-injury activates dermal fibroblasts through growth factor signaling (particularly TGF-β1), stimulating a burst of new collagen production. The number and activity of fibroblasts declines with age, which is why laser treatments become increasingly valuable as skin matures.

Fluence

The energy density delivered per unit area in a laser treatment, expressed in millijoules per square centimeter (mJ/cm²) or millijoules per pulse (mJ/pulse). Fluence is one of the most important treatment parameters in laser medicine — too low produces no therapeutic effect; too high risks tissue damage. OYAY LAB devices operate within clinically validated fluence ranges: 3–12mJ/pulse (Iris Ice Plus), 2–7mJ/pulse (Dora), 6–12mJ/pulse (RelaxLight), and 0.5–1W (Nova).

Fractional Photothermolysis

A laser delivery technique in which energy is delivered in a grid of discrete, microscopic columns (Microscopic Treatment Zones) rather than uniformly across the entire skin surface. Developed at Harvard Medical School (Manstein & Anderson, 2004), fractional photothermolysis enables significant dermal remodeling with minimal downtime because the untreated tissue between columns provides a biological reservoir for rapid repair. All OYAY LAB home laser devices use fractional delivery. Treatments may be non-ablative (NAFL) or ablative (AFL) — OYAY LAB home devices use exclusively non-ablative fractional technology.

H

Hyperpigmentation

Darkening of skin caused by excess melanin production or irregular melanin distribution. Common causes include UV exposure, hormonal changes (melasma), post-inflammatory responses (PIH from acne or injury), and aging. The OYAY LAB Dora device (1927nm) targets hyperpigmentation at the dermal-epidermal junction, accelerating melanin metabolism and dispersion for a more even skin tone.

I

IEC 60825

The international standard published by the International Electrotechnical Commission (IEC) that specifies safety requirements for laser products. Products are classified from Class 1 (safest) to Class 4 (highest risk). Class 1 certification — held by all OYAY LAB home devices — means the accessible laser radiation during all conditions of normal use is below the threshold that can cause biological harm. This is the mandatory certification for consumer laser devices in most international markets.

M

Melanin

The pigment molecule produced by melanocytes in the basal layer of the epidermis and upper dermis. Melanin determines skin color and provides UV protection. In aesthetic laser medicine, melanin is both a therapeutic target (for pigmentation correction) and a competing absorber that must be accounted for in treatment planning. The 1927nm wavelength used in the OYAY LAB Dora is selected for its favorable ratio of dermal water absorption to melanin absorption, enabling safe pigmentation treatment across a broad range of skin tones when used correctly.

Microscopic Treatment Zone (MTZ)

The individual column of thermally modified tissue created by a single fractional laser micro-beam. Each MTZ is surrounded by intact, untreated tissue. MTZ diameter, depth, and density are key treatment parameters. In OYAY LAB home devices, MTZ characteristics are controlled by the energy level and treatment zone setting selected by the user.

N

Non-Ablative Fractional Laser (NAFL)

A laser treatment modality that combines fractional delivery with a wavelength that does not ablate (remove) the epidermis. NAFL creates columns of thermal micro-injury in the dermis while preserving the overlying epidermis — stimulating collagen and elastin synthesis without the healing period required after ablative treatments. NAFL is the technology platform underlying the OYAY LAB Iris Ice Plus (1450nm) and Dora (1927nm) devices. It represents the optimal balance between efficacy and safety for at-home use.

P

Photobiomodulation (PBM)

The use of low-level laser or light energy to modulate biological processes without causing thermal injury. PBM operates through photochemical mechanisms — photons are absorbed by mitochondrial photoacceptors (primarily cytochrome c oxidase), triggering cascades that increase cellular energy (ATP), reduce oxidative stress, and modulate inflammatory signaling. The OYAY LAB RelaxLight (940nm) uses photobiomodulation principles to achieve anti-inflammatory and analgesic effects.

Pulse Width (Pulse Duration)

The duration of a single laser pulse, measured in seconds, milliseconds, microseconds, nanoseconds, or picoseconds. Pulse width determines whether energy is delivered thermally (longer pulses; milliseconds) or photomechanically (shorter pulses; nanoseconds, picoseconds). For collagen remodeling, millisecond-range pulses are optimal. For pigmentation and tattoo removal, nanosecond (Q-switched) or picosecond pulses are used — the latter is the basis of the OYAY LAB Professional Picosecond Nd:YAG system.

S

Selective Photothermolysis

The foundational principle of modern medical laser treatment, described by Anderson and Parrish (Harvard Medical School, 1983). Selective photothermolysis states that a laser wavelength, pulse duration, and fluence can be chosen such that a specific chromophore (e.g., melanin, hemoglobin, water) absorbs laser energy and is thermally damaged, while surrounding tissue is spared. OYAY LAB device wavelengths are engineered around this principle to selectively target specific skin concerns without off-target tissue damage.

W

Wavelength

The distance between successive peaks of a light wave, expressed in nanometers (nm) for visible and near-infrared light. In laser medicine, wavelength is the primary parameter that determines which chromophore absorbs the energy and how deeply it penetrates tissue. Shorter wavelengths (400–700nm) penetrate superficially; longer wavelengths (800–2000nm) penetrate more deeply into the dermis. OYAY LAB devices use wavelengths ranging from 415nm (superficial blue light for acne) to 1927nm (dermal water targeting for pigmentation and resurfacing).

This glossary is provided by OYAY LAB for educational purposes. The definitions reflect current consensus in photomedicine and laser dermatology literature. For clinical questions regarding your specific skin condition, consult a licensed dermatologist.